Enteropathy Associated with Olmesartan

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Enteropathy Associated with Olmesartan

The recognition of an enteropathy caused by olmesartan is recent. It was first described in 2012 by the Mayo Clinic, which presented 22 clinical cases. Olmesartan is a highly prescribed drug and the differential diagnosis of a sprue-like enteropathy is very wide, so it is important to be aware of this pathology. We report a case of a 67-years-old man, with arterial hypertension under treatment ...

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Immunopathogenesis of olmesartan-associated enteropathy.

BACKGROUND Olmesartan-associated enteropathy (OAE) is characterised by diarrhoea, nausea, vomiting, abdominal pain, weight loss and severe sprue-like enteropathy, all of which are resolved after discontinuation of olmesartan medoximil. AIM To determine the mechanistic similarities of OAE with coeliac sprue. METHODS Duodenal biopsies were extracted from OAE patients before (n = 11) or after ...

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Severe sprue-like enteropathy associated with olmesartan.

OBJECTIVE To report the response to discontinuation of olmesartan, an angiotensin II receptor antagonist commonly prescribed for treatment of hypertension, in patients with unexplained severe spruelike enteropathy. PATIENTS AND METHODS All 22 patients included in this report were seen at Mayo Clinic in Rochester, Minnesota, between August 1, 2008, and August 1, 2011, for evaluation of unexpla...

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Olmesartan Enteropathy

Celiac disease is an immune-mediated small intestinal mucosal disorder with characteristic, but nonspecific histopathological changes. A number of heterogeneous disorders may produce similar changes in small bowel biopsies, but these fail to respond to a gluten-free diet. Recently, it has become increasingly appreciated that different medications may cause this sprue-like intestinal disease, in...

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Systematic review: Sprue-like enteropathy associated with olmesartan.

BACKGROUND The onset of a sprue-like enteropathy in association with olmesartan therapy has been recently reported. AIMS To perform a systematic review of the literature and describe three additional cases of olmesartan-associated enteropathy. METHODS Electronic and manual bibliographic searches were performed to identify original reports in which subjects who were undertaking olmesartan de...

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ژورنال

عنوان ژورنال: GE Portuguese Journal of Gastroenterology

سال: 2016

ISSN: 2341-4545

DOI: 10.1016/j.jpge.2015.10.007